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New cell patch aims to ease knee arthritis pain in phase 3 trial

NCT ID NCT06549686

First seen Nov 24, 2025 · Last updated May 22, 2026 · Updated 18 times

Summary

This study tests whether a special sheet of donated cartilage cells (CLS2901C) can improve knee pain and function in people with osteoarthritis. About 96 adults aged 20 to 79 with moderate to severe knee arthritis will receive either knee realignment surgery plus the cell sheet, or surgery alone. The main goal is to see if the cell sheet leads to better knee scores one year after treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ebina General Hospital/Ebina Medical Plaza

    RECRUITING

    Ebina, Kanagawa, 243-0433, Japan

  • Juntendo University Hospital

    RECRUITING

    Bunkyō-Ku, Tokyo, 113-8431, Japan

  • Tokai University Hospital

    RECRUITING

    Isehara, Kanagawa, 259-1193, Japan

  • Yokohama City University Medical Center

    RECRUITING

    Yokohama, Kanagawa, 232-0024, Japan

  • Yokohama Minami Kyousai Hospital

    RECRUITING

    Yokohama, Kanagawa, 236-0037, Japan

  • Yokohama Sekishinkai Hospital

    RECRUITING

    Yokohama, Kanagawa, 230-0062, Japan

Conditions

Explore the condition pages connected to this study.