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Knee injection showdown: which works better for arthritis pain?

NCT ID NCT07194135

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two different knee injections for people with knee osteoarthritis. One injection was a common steroid (triamcinolone), and the other was a long-acting anti-inflammatory (tenoxicam). The goal was to see which one reduced pain and improved knee function better, while also checking for side effects like blood sugar changes. 100 adults aged 45 to 75 with moderate knee arthritis took part.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Nov 2024

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

45 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 45 to 75 years * Radiographically confirmed knee osteoarthritis (Kellgren-Lawrence grade II-III) * Persistent knee pain for at least 3 months despite oral non-steroidal anti-inflammatory drugs * Ability to provide informed consent Exclusion Criteria: * Prior intra-articular injection within the past 6 months * Inflammatory arthritis (e.g., rheumatoid arthritis, gout) * Advanced knee osteoarthritis (Kellgren-Lawrence grade IV) * Active joint or systemic infection * Bleeding disorder or anticoagulant use contraindicating injection * Uncontrolled diabetes mellitus * Known hypersensitivity to tenoxicam or triamcinolone acetonide

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Benha University Hospitals, Department of Orthopedics and Rheumatology

    Banhā, Qalyubia Governorate, 13511, Egypt

More trials for these conditions

Other studies related to the condition(s) this trial covers.