Knee injection showdown: which works better for arthritis pain?
NCT ID NCT07194135
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two different knee injections for people with knee osteoarthritis. One injection was a common steroid (triamcinolone), and the other was a long-acting anti-inflammatory (tenoxicam). The goal was to see which one reduced pain and improved knee function better, while also checking for side effects like blood sugar changes. 100 adults aged 45 to 75 with moderate knee arthritis took part.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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100 people
The number who actually took part.
- Started
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Nov 2024
- Finished
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Apr 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 45 to 75 years * Radiographically confirmed knee osteoarthritis (Kellgren-Lawrence grade II-III) * Persistent knee pain for at least 3 months despite oral non-steroidal anti-inflammatory drugs * Ability to provide informed consent Exclusion Criteria: * Prior intra-articular injection within the past 6 months * Inflammatory arthritis (e.g., rheumatoid arthritis, gout) * Advanced knee osteoarthritis (Kellgren-Lawrence grade IV) * Active joint or systemic infection * Bleeding disorder or anticoagulant use contraindicating injection * Uncontrolled diabetes mellitus * Known hypersensitivity to tenoxicam or triamcinolone acetonide
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Benha University Hospitals, Department of Orthopedics and Rheumatology
Banhā, Qalyubia Governorate, 13511, Egypt
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Other studies related to the condition(s) this trial covers.
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