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Mind over matter? study tests if hope helps healing in knee pain

NCT ID NCT07618403

Knowledge-focused Sponsor: Gazi University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a person's expectations before starting physical therapy can predict how much they will benefit from it. Researchers will track 84 adults over 50 with knee osteoarthritis as they go through 15 sessions of standard physical therapy. The goal is to see if those with higher hopes actually experience less pain and better function afterward.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors tailor physical therapy plans based on a patient's expectations, potentially improving outcomes for knee osteoarthritis.
What could go wrong
This is a small, early-stage observational study, not a treatment trial. It may not find a clear link, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 84 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients aged 50 years and older who present with knee pain and are found to have grade 2 or higher gonarthrosis according to the Kellgren-Lawrence classification on X-ray imaging.

Ages

50 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Agreeing to participate in the study * Being over 50 years of age * Having a clinically and radiographically confirmed diagnosis of knee osteoarthritis * Having grade 2-3-4 knee osteoarthritis according to the Kellgren-Lawrence grading system * Being literate Exclusion Criteria: * Previous knee surgery * Conditions that prevent exercise (such as incurable malignancy, active systemic infection, non-union fracture) * Presence of accompanying neurological disease affecting the lower extremity * Severe cognitive impairment (neuropsychiatric disease or condition that will impede cooperation, such as psychosis, dementia) * History of having received injections or other procedures to the knee joint or physical therapy within the last 6 months

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Conditions

The condition(s) this trial relates to.

osteoarthritis, knee

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Gonarthrosis; primary Patients' expectations Physical therapy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Gazi University

    RECRUITING

    Ankara, Yenimahalle, 06170, Turkey (Türkiye)

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