Women's knee injury risk: new study probes hormone link

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Woman between 18 and 40 years old * No history of surgery of the 2 lower limbs * No change in contraceptive method in the last 6 months * Signature of the informed consent * Affiliation to the social security system * To be at Day 14 of her menstrual cycle (+/-1 day) (the first day of the cycle (Day1) being considered as the first day of the menstrual period), except for those on micro-progestative contraception not regulated By inclusion group: \- For women without hormonal contraception: No method of contraception Or a copper intrauterine device Regular cycles of 26 to 33 days \- For women on estrogen-progestin contraception: Correct use of the estrogen-progestin pill according to the MA Or wearing a vaginal ring according to the MA protocol Or wearing a contraceptive skin patch according to the MA protocol Regular cycles of 26 to 33 days \- For women on micro-progestin contraception : Continuous use of the micro-progestogen pill Or wearing a subcutaneous hormonal implant, Exception: women on micro-progestin contraception who are not regulated: * They may have an irregular cycle or no cycle to be included * They can be included on any day if they have no cycle Exclusion Criteria: * Pregnancy or breastfeeding in progress * Hormonal intrauterine device or injectable contraception * Menopause (defined as no menstruation for one year) * Surgery: tubal ligation, oophorectomy, adnexectomy, hysterectomy * History of microcrystalline or infectious pathology localized to the knee * History of systemic or localized inflammatory joint disease of the knee * History of fracture, severe sprain or dislocation of the knee joint * History of osteoarticular or congenital diseases that may lead to laxity (Marfan syndrome, trisomy 21, Ehlers-Danlos syndrome...) * Sign of hyperlaxity evaluated by a Beighton score higher than 4 (see appendix) * BMI \> 25 * Daily alcohol consumption above the thresholds recommended by Public Health in France (more than 2 glasses per day) * Woman unable to understand the protocol * Intense or unusual physical exercise during the last 72 hours (e.g.: marathon, triathlon, competitive cycling race...) * Woman under guardianship, curatorship or deprived of liberty