Could a dissolving nail fix knee fractures without metal?
NCT ID NCT06138548
First seen Jun 25, 2026 · Last updated Aug 18, 2026 · Updated 3 times
Summary
This study tests a special nail made from a fiber-reinforced material that integrates with bone over time, instead of staying in the body like metal. Ten people with knee fractures will get the implant and be followed for up to two years. The goal is to see if it reduces pain and improves knee function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- OSSIOfiber® Trimmable Fixation Nail (a bio-integrative, fiber-reinforced device)
- What this could lead to
- If it works, this could offer a new, less invasive way to treat knee fractures that may avoid metal implants and reduce long-term complications.
- What could go wrong
- This is a very small early study with only 10 participants, so results may not apply to everyone. The device is new and long-term outcomes are unknown.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Those who have subchondral insufficiency of the knee with tibial or femoral overload.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Has had knee pain in study knee lasting at least 3 months 2. Candidate for knee arthroscopy due to meniscal tear, loose body, unstable articular cartilage or mechanical symptoms. Exclusion Criteria: 1. Current tobacco use or has quit within 3 months of study enrolment. 2. Substance abuse history. 3. Diabetes mellitus, HbA1c\>8 4. High surgical risk due to pre-existing conditions. 5. Currently pregnant or has plans to become pregnant prior to surgery. 6. Active infection or history of chronic infection in study knee. 7. Will require concomitant procedures within study knee, including but not limited to ligament reconstruction, tendon repair, meniscus repair, microfracture, osteotomy, or osteochondral transplantation. (Meniscal tears, including chronic, are acceptable if no repair is required)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Rush University
Chicago, Illinois, 60612, United States
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Stanford University
Stanford, California, 94305, United States
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