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New pill shows promise for severe hair loss, but trial cut short

NCT ID NCT05496426

First seen May 30, 2026 · Last updated Jun 22, 2026 · Updated 3 times

Summary

This study tested an oral drug called KL130008 in 114 adults with severe alopecia areata, a condition causing significant scalp hair loss. The goal was to see if the drug could regrow hair to at least 80% coverage. However, the trial was terminated early, so the full results are not available.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • The First Affiliated Hospital of Sun Yat-sen University

    Guangzhou, Guangzhou, 510080, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

KL130008 capsule

What this could lead to

If successful, this could point toward a new oral treatment option for people with severe alopecia areata, potentially regrowing significant scalp hair.

What could go wrong

The trial was terminated early, so results are limited. It is a Phase 2 study, meaning it is still early and may not confirm effectiveness or safety in larger groups.

Conditions

The condition(s) this trial relates to.

alopecia areata disorder of pilosebaceous unit hypotrichosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.