Hormone shot reveals long COVID's hidden impact on the brain
NCT ID NCT07224490
First seen Nov 04, 2025 · Last updated Jun 23, 2026 · Updated 32 times
Summary
This study gives a single injection of kisspeptin, a natural hormone, to 40 people with and without Long COVID. Researchers take blood samples every 10 minutes to measure how the brain's reproductive hormone system responds. The goal is to learn whether Long COVID changes this system, not to treat any condition.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Kisspeptin (a hormone injection)
What this could lead to
If successful, this could help explain how Long COVID affects the brain's reproductive hormone system, pointing toward future treatments.
What could go wrong
This is a very early Phase 1 study with only 40 people. It is designed to measure hormone levels, not to test a treatment, so direct benefits are unlikely.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.