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Engineered t cells take on deadly childhood brain cancer

NCT ID NCT05478837

First seen Mar 16, 2026 · Last updated May 18, 2026 · Updated 8 times

Summary

This early-stage trial tests a new treatment for people with a rare, aggressive brain tumor called H3.3K27M-mutated diffuse midline glioma. The treatment uses the patient's own immune cells, which are modified in a lab to better recognize and attack the tumor. The main goals are to check safety and find the best dose, with only 12 participants enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94143, United States

Conditions

Explore the condition pages connected to this study.