Scientists test immune 'Gas Pedal' drug to fight tough kidney cancers
NCT ID NCT03092856
Summary
This study is testing if adding an experimental immune-stimulating drug (PF-04518600) to a standard cancer drug (axitinib) works better for controlling advanced kidney cancer that has spread. The trial involves 62 patients whose cancer worsened after prior immunotherapy. Participants are randomly assigned to receive either the two-drug combination or axitinib with a placebo to see which approach better stops cancer growth.
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Contacts and locations
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Locations
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Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center
Cleveland, Ohio, 44195, United States
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Los Angeles County-USC Medical Center
Los Angeles, California, 90033, United States
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Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210, United States
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USC / Norris Comprehensive Cancer Center
Los Angeles, California, 90033, United States
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USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California, 92663, United States
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University of California Davis Comprehensive Cancer Center
Sacramento, California, 95817, United States
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University of Kansas Cancer Center
Kansas City, Kansas, 66160, United States
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University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232, United States
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University of Virginia Cancer Center
Charlottesville, Virginia, 22903, United States
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Weill Cornell Medical College, New York- Presbyterian Hospital
New York, New York, 10065, United States
Conditions
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