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Keto diet shows promise for stabilizing brain networks in mental illness

NCT ID NCT05268809

First seen Jan 12, 2026 · Last updated May 25, 2026 · Updated 16 times

Summary

This study tested whether a 4-week ketogenic diet (very low carb, high fat) could improve brain network stability and thinking skills in 71 adults with schizophrenia or bipolar disorder. The diet aims to provide an alternative brain fuel (ketones) that may bypass problems with glucose metabolism common in these conditions. Participants were randomly assigned to either the keto diet or their usual diet, and researchers measured brain scans, body changes, inflammation, and insulin resistance.

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Contacts and locations

Locations

  • San Francisco VA Medical Center

    San Francisco, California, 94121, United States

Conditions

Explore the condition pages connected to this study.