Keto Diet's impact on cholesterol examined in tiny study
NCT ID NCT03901014
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study looked at how a very low-carbohydrate (ketogenic) diet changes the way the body makes cholesterol, fatty acids, and ketones. Four healthy men followed both a standard American diet and a ketogenic diet to compare the effects. The goal was to understand the body's fat and cholesterol production, not to treat any disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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4 people
The number who actually took part.
- Started
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Mar 2019
- Finished
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Apr 2019
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Male participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male * 18-50 years old Exclusion Criteria: * Use of nicotine products * Has dietary restrictions * Lactose intolerance * History of GI disorders, diabetes, liver, kidney, or thyroid disorders * Taking hypolipidemic, anti-diabetic, anti-hypertensive, or anti-depression medication * Screening plasma triglyceride \< 50mg/dl or \>500mg/dl * Screening glucose \> 125mg/dl * Screening total and LDL-Cholesterol over 95th %tile for age and sex * BP \> 160/95 mmHg * Weight loss/gain \> 5% in the previous 3 months (self-reported)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Touro University California
Vallejo, California, 94592, United States
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Other studies related to the condition(s) this trial covers.