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Ketamine may cut opioid needs for trauma patients

NCT ID NCT04833816

First seen Feb 04, 2026 · Last updated Jun 13, 2026 · Updated 16 times

Summary

This study looked at whether giving a low dose of ketamine continuously could lower the amount of strong painkillers (opioids) needed by people with serious injuries. The goal was to see at least a 25% reduction in opioid use over 48 hours while still controlling pain just as well. The trial involved 140 adults with multiple severe injuries and compared ketamine to a placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Service Anesthésie Réanimation - Hôpital nord

    Marseille, 13015, France

Conditions

The condition(s) this trial relates to.

agnosia injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.