Low-Dose ketamine may reduce Post-Surgery pain in ectopic pregnancy patients
NCT ID NCT06559280
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether giving a tiny, non-anesthetic dose of ketamine during surgery could lower pain sensitivity right after the operation. It involved 84 women having laparoscopic salpingectomy for ectopic pregnancy. Researchers measured pain sensitivity using a questionnaire before and after surgery. The goal was to see if this simple addition to anesthesia could make recovery more comfortable.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Early phase 1
The earliest testing in people: a first look at safety, in a very small group.
- Participants
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84 people
The number who actually took part.
- Started
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Aug 2024
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age\>18 years old * BMI 18-30 kg/m2; * American Society of Anesthesiologists (ASA) classification I and II * The patient was diagnosed with ectopic pregnancy through ultrasound examination, and it was confirmed that there was no embryo or gestational sac in the uterus; The patient has indications for laparoscopic ectopic pregnancy surgery; * All patients are scheduled to undergo laparoscopic salpingectomy for treatment Normal mental state; * No cognitive impairment; * Normal communication skills, no speech barriers Exclusion Criteria: * Individuals with severe organ dysfunction such as heart, lungs, liver, and kidneys; * Individuals with serious mental illnesses; * Long term use of sedatives and analgesics or long-term alcoholism and smoking; * History of allergy to ketamine and related drugs * There is a serious risk of hypertension or elevated intracranial pressure, as well as contraindications for the use of ketamine in cases of hyperthyroidism Refuse to join the trial; * Patients with a history of other chronic pain diseases.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fuzhou University affiliated Provincial Hospital
Fuzhou, Fujian, 350001, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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