Can fillers restore a youthful face after weight loss? new study investigates
NCT ID NCT07186595
First seen Jun 27, 2026 · Last updated Aug 11, 2026 · Updated 2 times
Summary
This study tests whether JUVÉDERM dermal fillers can safely improve facial volume and skin quality in adults who have lost weight through medical programs. About 75 participants will receive injections in their mid-face and other areas. Researchers will measure satisfaction and track any side effects.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- JUVÉDERM dermal fillers (hyaluronic acid injections)
- What this could lead to
- If it works, this could show that JUVÉDERM fillers safely improve facial volume and satisfaction for people who lose weight.
- What could go wrong
- This is a small, early-phase study with no comparison group. Results may not apply to everyone, and side effects like swelling or bruising are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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75 people
The number who actually took part.
- Started
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Sep 2025
- Finished
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Jul 2026
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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22 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Must meet at least 3 of the following criteria for treatment in the face with at least 2 JUVÉDERM products, per investigator's assessment: * Minimal, moderate, or severe on Allergan Temple Hollowing Scale (ATHS) * Moderate or severe for both eyes on Allergan Infraorbital Hollow Scale (AIHS) * Moderate or severe on Allergan Cheek Smoothness Scale (ACSS) * Moderate, significant, or severe on Mid-face Volume Deficit Scale (MFVDS) * Moderate or severe on Nasolabial Fold Severity Scale (NLFSS) * Minimal, mild, or moderate on Allergan Lip Fullness Scale 2 (ALFS2) * Moderate or severe on Allergan Chin Retrusion Scale (ACRS) * Moderate or severe on Allergan Loss of Jawline Definition Scale (ALJDS) * Must be in good health as determined by subject's medical history, physical examination, and vital sign measurements. Exclusion Criteria: * Prior treatment with non-permanent soft tissue fillers or fat-reducing injectables in the face or neck within 12 months prior to screening. * Excessively loose skin in the face and/or neck. * Tendency to develop hypertrophic scarring and/or keloid scarring.
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Advanced Dermatology - Lincolnshire /ID# 277036
Lincolnshire, Illinois, 60069, United States
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Bellaire Dermatology Associates /ID# 278180
Bellaire, Texas, 77401, United States
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Delricht Research - Prytania Street - New Orleans /ID# 277039
New Orleans, Louisiana, 70115, United States
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H and H Research LLC /ID# 277084
Metairie, Louisiana, 70001, United States
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Kian Aesthetic Institute /ID# 277045
Los Angeles, California, 90025, United States
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Monarch Plastic Surgery and Skin Renewal Center /ID# 278182
Atlanta, Georgia, 30328, United States
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Pacific Clinical Innovations /ID# 277026
Vista, California, 92083, United States
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Skin Research Institute LLC /ID# 277038
Coral Gables, Florida, 33146-1837, United States
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SkinDC /ID# 277062
Arlington, Virginia, 22209, United States
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West Dermatology La Jolla /ID# 277034
San Diego, California, 92121, United States
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