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New hope for KRAS lung cancer: targeted pill tested in phase 3 trial

NCT ID NCT02152631

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 3 study tests whether the targeted drug abemaciclib can help people with stage IV lung cancer that has a KRAS mutation and has worsened after chemotherapy. About 450 participants received either abemaciclib or another targeted drug (erlotinib), both alongside best supportive care. The main goal is to see if abemaciclib helps people live longer.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
abemaciclib (a targeted cancer pill)
What this could lead to
If it works, this could offer a new treatment option for people with a specific type of advanced lung cancer that has stopped responding to chemotherapy.
What could go wrong
This is a late-stage trial, but the drug may not improve survival compared to the current standard. Side effects from targeted therapies can be serious.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

453 people

The number who actually took part.

Started

Oct 2014

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Have confirmed diagnosis of stage IV non-small cell lung cancer (NSCLC) according to the American Joint Committee on Cancer Staging Handbook. * Determined to have detectable mutations in codons 12 or 13 of the kirsten rat sarcoma (KRAS) oncogene by an investigational assay at the study central laboratory. A KRAS positive mutation result in codons 12 or 13 of the KRAS oncogene from tumor tissue per local laboratory will be permitted in no more than 10% of randomized participants. * Have progressed after platinum-based chemotherapy (with or without maintenance therapy) AND have received one additional therapy which may include an immune checkpoint inhibitor or other anti-cancer therapy for advanced and/or metastatic disease OR is judged by the physician as ineligible for further standard second-line chemotherapy. Participants who have progressed after platinum-based chemotherapy and an immune checkpoint inhibitor (immunotherapy) e.g. pembrolizumab or nivolumab alone or in combination with other agents are eligible. * Have measureable disease as defined by the Response Evaluation Criteria in Solid Tumors (RECIST 1.1). * Have a performance status (PS) of 0 to 1 on the Eastern Cooperative Oncology Group (ECOG) scale. * Have discontinued all previous therapies for cancer (including chemotherapy, radiotherapy, immunotherapy, and investigational therapy) for at least 21 days for myelosuppressive agents or 14 days for nonmyelosuppressive agents prior to receiving study drug. Exclusion Criteria: * Have received treatment with a drug that has not received regulatory approval for any indication within 14 or 21 days of the initial dose of study drug for a nonmyelosuppressive or myelosuppressive agent, respectively. * Have a personal history of any of the following conditions: presyncope or syncope of either unexplained or cardiovascular etiology, ventricular arrhythmia (including but not limited to ventricular tachycardia and ventricular fibrillation), or sudden cardiac arrest. * Have the presence of unstable central nervous system (CNS) metastasis. History of CNS metastasis or stable CNS metastases is allowed (no longer requiring active therapy such as steroid medications). Participants with a history of CNS metastases must have a brain scan (for example, magnetic resonance imaging \[MRI\]) within 28 days of randomization to document stability, even if there have been no changes in symptoms. * Have previously completed or withdrawn from this study or any other study investigating a cyclin-dependent kinase 4 (CDK4) and cyclin-dependent kinase 6 (CDK6) inhibitors, or have received treatment with a prior CDK4 and CDK6 inhibitors.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alegent Immanuel Cancer Center

    Englewood, Colorado, 80112, United States

  • Arkhangelsk Regional Clinical Oncology Dispensary

    Arkhangelsk, 163045, Russia

  • Associação Hospital de Caridade Ijuí

    Ijuí, 98700 000, Brazil

  • Billings Clinic Research Center

    Billings, Montana, 59101, United States

  • Boca Raton Regional Hospital

    Boca Raton, Florida, 33486, United States

  • Broome Oncology

    Johnson City, New York, 13790, United States

  • CBCC Global Research, Inc.

    Los Angeles, California, 90024, United States

  • Cancer Care Associates Medical Group

    Los Angeles, California, 90095, United States

  • Cancer Care Northwest

    Valley, Washington, 99216, United States

  • Cancer Center of Kansas, P.A.

    Wichita, Kansas, 67214, United States

  • Central Baptist Hospital

    Lexington, Kentucky, 40503, United States

  • Central Coast Medical Oncology Corporation

    Los Angeles, California, 90024, United States

  • Chattanooga Oncology Hematology Associates

    Chattanooga, Tennessee, 37404, United States

  • Chattanooga Oncology Hematology Associates

    Nashville, Tennessee, 37203, United States

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Dartmouth Hitchcock Medical Center

    Lebanon, New Hampshire, 03756, United States

  • Dignity Health Care Institute

    Sacramento, California, 95816, United States

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician

    Berazategui, B1884BBF, Argentina

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    Rosario, S2000DSV, Argentina

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    Linz, 4020, Austria

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    São Paulo, 01246000, Brazil

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    Beijing, 100021, China

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    Beijing, 100730, China

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    Dijon, 21034, France

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    Saint-Brieuc, 22027, France

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    Ciudad Autonoma Buenos Aires, 1025, Argentina

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    Ciudad Autonoma Buenos Aires, 1093, Argentina

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    Ciudad Autonoma Buenos Aires, C1181AAX, Argentina

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    Rosario, 2000, Argentina

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    Viedma, 8500, Argentina

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    Graz, 8036, Austria

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    Linz, 4021, Austria

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    Salzburg, 5020, Austria

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    Porto Alegre, 90610-970, Brazil

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    Rio de Janeiro, 20231-050, Brazil

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    Salvador, 41253-190, Brazil

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    Sao Jose Rio Preto, 15090-000, Brazil

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    Beijing, 100071, China

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    Changchun, 130012, China

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    Changzhou, 213000, China

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    Chengdu, 610041, China

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    Haikou, 570311, China

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    Hangzhou, 310022, China

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    Hefei, 230001, China

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    Nanning, 530021, China

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    Shanghai, 200030, China

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    Shenyang, 100042, China

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    Bron, 69677, France

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    Grenoble, 38043, France

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    Lille, 59037, France

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    Marseille, 13015, France

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    Poitiers, 86021, France

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    Rennes, 35033, France

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    Saint-Priest-en-Jarez, 42270, France

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    Toulouse, 31059, France

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    Vantoux, 57070, France

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    Berlin, 14165, Germany

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    Gera, 07548, Germany

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    Großhansdorf, 22927, Germany

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    Hamburg, 21075, Germany

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    Hanover, 30459, Germany

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    Heidelberg, 69126, Germany

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    Immenhausen, 34376, Germany

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    Nuremberg, 90419, Germany

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    Regensburg, 93053, Germany

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    Rosenheim, 83022, Germany

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    Tübingen, 72076, Germany

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    Ulm, 89081, Germany

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    Athens, 11522, Greece

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    Athens, 11527, Greece

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    Athens, 18537, Greece

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    Heraklion, 71110, Greece

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    Pátrai, 26504, Greece

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    Holon, 5822012, Israel

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    Petah Tikva, 4941492, Israel

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    Catania, 95125, Italy

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    Genova, 16132, Italy

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    Livorno, 57124, Italy

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    Parma, 43100, Italy

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    Rome, 00152, Italy

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    Amagasaki, 660-0892, Japan

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    Asahikawa, 070-8644, Japan

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    Bunkyō City, 113-8431, Japan

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    Bunkyō City, 113-8677, Japan

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    Fukuoka, 811-1395, Japan

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    Habikino, 583-8588, Japan

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    Hirakata, 573-1191, Japan

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    Hiroshima, 734-8551, Japan

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    Hyōgo, 6608550, Japan

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    Kanazawa, 920-8641, Japan

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    Kashiwa, 277 8577, Japan

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    Kishiwada, 596-8501, Japan

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    Kitaadachi-Gun, 362-0806, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Kobe, 650-0047, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Kōtoku, 135-8550, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Kurashiki, 710-8602, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Matsuyama, 791-0280, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Nagasaki, 852-8501, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Nagoya, 464-8681, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Nagoya, 466-8560, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Natori, 981-1293, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Okayama, 700-8558, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Osaka, 534-0021, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Osaka, 537-8511, Japan

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    Osaka, 545-8586, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Sakai, 5918555, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Sayama, 589-8511, Japan

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    Sendai, 980-0873, Japan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Shinjuku-ku, 160-0023, Japan

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    Sunto-Gun, 411-8777, Japan

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    Ube, 755-0241, Japan

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    Utsunomiya, 320-0834, Japan

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    Wakayama, 641-8510, Japan

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    Yokohama, 236-0004, Japan

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    Yonago, 683-0826, Japan

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    Yufu-shi, 8795593, Japan

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    Gdansk, 80-219, Poland

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    Lodz, 90-242, Poland

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    Olsztyn, 10-357, Poland

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Radom, 26-617, Poland

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Szczecin, 70-891, Poland

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Baia Mare, 430031, Romania

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Bucharest, 022328, Romania

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Cluj-Napoca, 400015, Romania

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Cluj-Napoca, 400058, Romania

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Craiova, 200347, Romania

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Kursk, 305035, Russia

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Goyang-si, 10408, South Korea

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Incheon, 21565, South Korea

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Seoul, 03722, South Korea

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Seoul, 05505, South Korea

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Seoul, 06351, South Korea

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Seoul, 06591, South Korea

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Seowon-Gu, 28644, South Korea

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Suwon, 16247, South Korea

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Ulsan, 44033, South Korea

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    A Coruña, 15006, Spain

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Barcelona, 08003, Spain

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    L'Hospitalet de Llobregat, 08907, Spain

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Madrid, 28040, Spain

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Madrid, 28041, Spain

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Madrid, 28050, Spain

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Málaga, 29010, Spain

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Seville, 41013, Spain

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Valencia, 46026, Spain

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Chiayi City, 613, Taiwan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Kaohsiung City, 82445, Taiwan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Kaohsiung City, 83301, Taiwan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Taichung, 40447, Taiwan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Taichung, 404, Taiwan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Tainan, 70403, Taiwan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Taipei, 10002, Taiwan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Taipei, 10449, Taiwan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Taipei, 11217, Taiwan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Zhonghe, 235, Taiwan

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Ankara, 06100, Turkey (Türkiye)

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Ankara, 06490, Turkey (Türkiye)

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Antalya, 07059, Turkey (Türkiye)

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Edirne, 22030, Turkey (Türkiye)

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Istanbul, 34020, Turkey (Türkiye)

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Istanbul, 34098, Turkey (Türkiye)

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Istanbul, 34890, Turkey (Türkiye)

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Izmir, 35100, Turkey (Türkiye)

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Dnipropetrovsk, 49102, Ukraine

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Kharkiv, 61070, Ukraine

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Kryvyi Rih, 50048, Ukraine

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Kyiv, 04107, Ukraine

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Lutsk, 63000, Ukraine

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Poltava, 36011, Ukraine

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Sumy, 40005, Ukraine

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Uzhhorod, 88000, Ukraine

  • For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

    Vinnitsa, 21029, Ukraine

  • For additional information regarding investigative sites for this trial, contact 1-888-545-5972 Mon - Fri, 9 AM to 4 PM or 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri, 9 AM to 5 PM Eastern Time or speak with your personal physician.

    Calgary, T2N 4N2, Canada

  • For additional information regarding investigative sites for this trial, contact 1-888-545-5972 Mon - Fri, 9 AM to 4 PM or 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri, 9 AM to 5 PM Eastern Time or speak with your personal physician.

    Edmonton, T6G 1Z2, Canada

  • For additional information regarding investigative sites for this trial, contact 1-888-545-5972 Mon - Fri, 9 AM to 4 PM or 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri, 9 AM to 5 PM Eastern Time or speak with your personal physician.

    Montreal, H2L 4M1, Canada

  • For additional information regarding investigative sites for this trial, contact 1-888-545-5972 Mon - Fri, 9 AM to 4 PM or 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri, 9 AM to 5 PM Eastern Time or speak with your personal physician.

    Toronto, M4N 3M5, Canada

  • For additional information regarding investigative sites for this trial, contact 1-888-545-5972 Mon - Fri, 9 AM to 4 PM or 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri, 9 AM to 5 PM Eastern Time or speak with your personal physician.

    Vancouver, V5Z 4E6, Canada

  • For additional information regarding investigative sites for this trial, contact 1-888-545-5972 Mon - Fri, 9 AM to 4 PM or 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri, 9 AM to 5 PM Eastern Time or speak with your personal physician.

    Winnipeg, R3A 1M3, Canada

  • Fort Wayne Oncology & Hematology

    Los Angeles, California, 90024, United States

  • Fundação Antonio Prudente - Hospital do Câncer A.C Camargo

    São Paulo, 01509-010, Brazil

  • H Lee Moffitt Cancer Center

    Tampa, Florida, 33612-9497, United States

  • Hadassah Medical Center - Ein Karem

    Jerusalem, 9112001, Israel

  • Halifax Medical Center

    Daytona Beach, Florida, 32114, United States

  • Highlands Oncology Group

    Fayetteville, Arkansas, 72703, United States

  • Hospital Bruno Born

    Lajeados, 95900-000, Brazil

  • Indiana University School of Medicine

    Indianapolis, Indiana, 46202, United States

  • Ingalls Memorial Hospital

    Harvey, Illinois, 60426, United States

  • Jewish Hospital

    Englewood, Colorado, 80112, United States

  • Kadlec Clinical Hematology & Oncology

    Kennewick, Washington, 99336, United States

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Krasnodar regional clinical hospital # 1 n. a. S. V. Ochapovskogo

    Krasnodar, 350086, Russia

  • Loma Linda University School of Medicine

    Loma Linda, California, 92350, United States

  • Mary Crowley Cancer Research Center

    Dallas, Texas, 75230, United States

  • Medical Oncology Hematology Consultants

    Newark, Delaware, 19713, United States

  • Meir Medical Center

    Kfar Saba, 4428164, Israel

  • Memorial Cancer Institute

    Pembroke Pines, Florida, 33028, United States

  • Mercy Medical Research Institute

    Springfield, Missouri, 65807, United States

  • Metro-West and Greater Boston CNS Research

    Framingham, Massachusetts, 01701, United States

  • Oklahoma Cancer Specialists & Research Institute, LLC

    Tulsa, Oklahoma, 74146, United States

  • Oncology Hematology Care Inc

    Cincinnati, Ohio, 45242, United States

  • Oncology Hematology West

    Englewood, Colorado, 80112, United States

  • Private clinic "Evimed"

    Chelyabinsk, 454048, Russia

  • Providence Cancer Center Oncology Hematology Care

    Portland, Oregon, 97213, United States

  • Republic clinical oncology dispensary of MoH of Bashkortostan Republic

    Ufa, 450054, Russia

  • Roper St. Francis Healthcare

    Charleston, South Carolina, 29401, United States

  • Russian oncological scientific centre n.a. N.N. Blokhin of RAMS

    Moscow, 115478, Russia

  • SMO Catholic Health Initiatives

    Englewood, Colorado, 80112, United States

  • SMO TRIO -Translational Research

    Los Angeles, California, 90024, United States

  • Saint-Petersburg city clinical oncology dispensary

    Saint Petersburg, 198255, Russia

  • Sheba Medical Center

    Tel Litwinsky, 5265601, Israel

  • Soroka Medical Center

    Beersheba, 8410101, Israel

  • St Joseph Cancer Center

    Englewood, Colorado, 80112, United States

  • St-Petersburg scientifical practical center of specialized kinds of medical care (oncological)

    Saint Petersburg, 197758, Russia

  • St. Bernards Medical Center

    Jonesboro, Arkansas, 72401, United States

  • St. Francis Medical Center

    Englewood, Colorado, 80112, United States

  • St. Joseph Heritage Medical Group

    Los Angeles, California, 90024, United States

  • Swedish Medical Center

    Seattle, Washington, 98104, United States

  • Tennessee Oncology PLLC

    Nashville, Tennessee, 37203, United States

  • UCLA Department of Medicine-Hematology/Oncology

    Los Angeles, California, 90024, United States

  • UPMC Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15213, United States

  • University Cancer & Blood Center, LLC

    Athens, Georgia, 30607, United States

  • University of California - San Diego

    La Jolla, California, 92037, United States

  • University of Iowa

    Iowa City, Iowa, 52242, United States

  • University of Louisville

    Louisville, Kentucky, 40202, United States

  • University of Vermont Medical Center

    Burlington, Vermont, 05401, United States

  • Utah Cancer Specialists

    Salt Lake City, Utah, 84106, United States

  • VA Caribbean Healthcare System

    San Juan, 00921-3201, Puerto Rico

  • Virginia Commonwealth University

    Richmond, Virginia, 23298, United States

  • Volgograd regional clinical oncology dispensary

    Volzhskiy, 404130, Russia

  • Walter Reed National Military Medical Center

    Bethesda, Maryland, 20889, United States

  • Weill Cornell Medical College

    New York, New York, 10065, United States

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