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Can a tiny patch tame period pain without drugs?

NCT ID NCT07825558

Symptom relief Sponsor: Signal Relief Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

Researchers are testing whether a thin, drug-free patch called the Jovi Patch can reduce menstrual pain and related symptoms. The patch contains conductive micro-metal particles and no medication, wires, or batteries. About 50 pre-menopausal women with moderate to severe menstrual discomfort will wear either the active patch or a look-alike sham patch during six menstrual cycles. After three cycles, those in the sham group switch to the active patch. The main question is whether more women using the active patch achieve at least a 30% reduction in pain scores compared with the sham group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a drug-free patch containing conductive micro-metal particles
What this could lead to
If it works, this could offer a drug-free option for easing menstrual pain and related symptoms.
What could go wrong
This is a small pilot study, so results may not hold up in larger trials. The patch may not outperform a sham, and skin irritation is a possible side effect.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pre-menopausal female subjects aged 18 -50 years. * Currently seeking treatment for general menstrual discomfort * NPRS scale score \> 4 at baseline. * Able and willing to provide informed consent in English without the assistance of an interpreter. Exclusion Criteria: * Receiving other investigational agents or on another clinical trial. * Subject has implantable pain device, pacemaker, defibrillator, or other neuromodulation implantable device. * Known to be pregnant, or plan to become pregnant in the next 6 months * Current Jovi/Signal Relief users

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Conditions

The condition(s) this trial relates to.

primary dysmenorrhea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

General menstrual discomfort

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Redeemer Health

    RECRUITING

    Meadowbrook, Pennsylvania, 19046, United States

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