New PKU pill shows promise in small teen trial
NCT ID NCT06637514
First seen Apr 24, 2026 · Last updated May 21, 2026 · Updated 4 times
Summary
This study tested an experimental drug called JNT-517 in 14 teenagers with phenylketonuria (PKU), a genetic condition that causes harmful buildup of an amino acid. Participants took either the drug or a placebo twice daily for 28 days to check safety and how the body processes the drug. The goal was to see if JNT-517 could lower phenylalanine levels, but the main focus was on safety and drug levels in the blood.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's Medical Center Dallas
Dallas, Texas, 75235, United States
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Murdoch Children's Research Institute
Parkville, Melbourne, Victoria, 3052, Australia
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Oregon Health and Science University
Portland, Oregon, 97239, United States
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University of Florida (UF) Health Shands Hospital
Gainesville, Florida, 32608, United States
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University of South Florida
Tampa, Florida, 33606, United States
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University of Texas Health (UTHealth) Science Center at Houston
Houston, Texas, 77030, United States
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Utah Health - The University of Utah Hospital
Salt Lake City, Utah, 84112, United States
Conditions
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