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New hope for rare, severe psoriasis: phase 3 trial underway

NCT ID NCT06295692

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 29 times

Summary

This study tests an experimental drug, JNJ-77242113, in 19 people with two rare and severe forms of psoriasis: generalized pustular psoriasis (GPP) and erythrodermic psoriasis (EP). The goal is to see if the drug can improve skin symptoms by week 16. Participants must have a diagnosis of GPP or EP and be candidates for phototherapy or systemic treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dokkyo Medical University Hospital

    Shimotsuga Gun, 321 0293, Japan

  • Fujita Health University Hospital

    Toyoake, 470-1192, Japan

  • Hospital of the University of Occupational and Environmental Health

    Kitakyushu-shi, 807-8556, Japan

  • Ichinomiya Municipal Hospital

    Ichinomiya, 491-8558, Japan

  • JR Sapporo Hospital

    Hokkaido, 060-0033, Japan

  • Kumamoto University Hospital

    Kumamoto, 860-8556, Japan

  • Mie University Hospital

    Tsu, 514 8507, Japan

  • Nagoya City University Hospital

    Nagoya, 467 8602, Japan

  • Public Interest Incorporated Foundation Nipoon Life Saiseikai Nippon Life Hospital

    Osaka, 550 0006, Japan

  • Teikyo University Hospital

    Itabashi Ku, 173 8606, Japan

  • Tohoku University Hospital

    Sendai, 980 8574, Japan

  • Tokyo Medical University Hospital

    Shinjuku, 160 0023, Japan

Conditions

Explore the condition pages connected to this study.