New hope for kids with arthritis: study tests best next drug after first fails
NCT ID NCT06654882
First seen Nov 01, 2025 · Last updated Jun 17, 2026 · Updated 36 times
Summary
This study looks at children with juvenile idiopathic arthritis (JIA) whose first treatment (a TNF inhibitor) did not work well enough. It compares three different medications to a second TNF inhibitor to see which works better at reducing disease activity. The goal is to find the best treatment path for each child. About 400 children aged 2 to 17 will take part.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Asklepios Children's Hospital
RECRUITINGSankt Augustin, North Rhine-Westphalia, 53757, Germany
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Hackensack Meridian Health - Joseph M. Sanzari Children's Hospital
RECRUITINGHackensack, New Jersey, 07601, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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IRCCS Giannina Gaslini Institute
RECRUITINGGenoa, Liguria, 16147, Italy
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Nationwide Children's Hospital
RECRUITINGColumbus, Ohio, 43205, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Francisco Pediatric Rheumatology
RECRUITINGSan Francisco, California, 94158, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Florida
RECRUITINGGainesville, Florida, 32610, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.