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Experimental blood cancer drug trial halted early – what happened?

NCT ID NCT04240704

First seen Nov 01, 2025 · Last updated May 19, 2026 · Updated 32 times

Summary

This early-stage study tested a new drug called JBH492 in 25 people with chronic lymphocytic leukemia (CLL) or non-Hodgkin's lymphoma (NHL) whose cancer had returned or stopped responding to prior treatments. The main goal was to check the drug's safety and find the right dose. The trial was terminated early, meaning it stopped before completion, so no final conclusions about effectiveness could be drawn.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Helsinki, FIN-00029, Finland

  • Novartis Investigative Site

    Dresden, 01307, Germany

  • Novartis Investigative Site

    Freiburg im Breisgau, 79106, Germany

  • Novartis Investigative Site

    Tel Aviv, 6423906, Israel

  • Novartis Investigative Site

    Chuo Ku, Tokyo, 104 0045, Japan

  • Novartis Investigative Site

    Singapore, 169608, Singapore

  • Novartis Investigative Site

    Seoul, 03080, South Korea

  • Novartis Investigative Site

    Barcelona, Catalonia, 08035, Spain

Conditions

Explore the condition pages connected to this study.