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New study pits JAK inhibitors against standard therapy for rare lung disease

NCT ID NCT07406932

First seen Feb 15, 2026 · Last updated Apr 30, 2026 · Updated 18 times

Summary

This study will compare two types of drugs—JAK inhibitors and calcineurin inhibitors—as first treatments for lung scarring (interstitial lung disease) caused by antisynthetase syndrome, a rare autoimmune condition. About 80 adults aged 18 to 75 with active lung disease who have not yet taken immunosuppressants will be enrolled. The goal is to see which drug better preserves lung function and improves survival over 12 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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