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Can big data straighten out strabismus treatment?
NCT ID NCT07763457
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This study builds a large registry of strabismus patients in Japan to evaluate how well different treatments—from surgery to simple observation—work in everyday practice. By analyzing outcomes for common, rare, and complex cases, researchers hope to identify which approaches succeed and why. The findings could help doctors predict surgical success and tailor care to each patient.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Strabismus surgery or conservative treatment (observation, prism therapy, orthoptic treatment)
- What this could lead to
- If successful, this could lead to better prediction of surgical outcomes and more personalized treatment decisions for strabismus patients.
- What could go wrong
- As a retrospective registry, it cannot prove cause and effect, and results may be limited by variations in clinical practice and data quality.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 10,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2032
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients diagnosed with strabismus who visited participating academic and high-volume eye centers in Japan for clinical evaluation, conservative treatment, or surgery.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients diagnosed with strabismus who underwent clinical evaluation or management (including observation for natural history, conservative treatment, or surgery) at participating institutions. * Observation period for common strabismus: A restricted recent timeframe (e.g., the most recent 3 years) to minimize selection bias. * Observation period for rare and complex strabismus: Up to 10 years (January 1, 2016, to the date of Institutional Review Board approval) to secure an adequate sample size. Exclusion Criteria: * Patients who formally opted out of data utilization for this study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Kyoto University Graduate School of Medicine
Kyoto, Kyoto, 606-8507, Japan
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