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New hope for kidney cancer: ivonescimab trial launches

NCT ID NCT06940518

First seen Jan 15, 2026 · Last updated Jun 23, 2026 · Updated 22 times

Summary

This Phase 2 trial is testing a drug called ivonescimab for people with advanced clear cell renal cell carcinoma (a type of kidney cancer) that has already been treated. The study aims to see if ivonescimab can help control the cancer and to check for side effects. About 40 participants will receive the drug intravenously at MD Anderson Cancer Center.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ivonescimab

What this could lead to

If successful, this could offer a new treatment option for people with advanced kidney cancer that has stopped responding to other therapies.

What could go wrong

This is an early Phase 2 trial with only 40 participants, so results may not apply to everyone. The drug may cause side effects or not work as hoped.

Conditions

The condition(s) this trial relates to.

renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.