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Experimental drug shows promise for rare lung condition in transplant patients

NCT ID NCT04239989

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 23 times

Summary

This early-stage study tested the safety of itacitinib, a drug that blocks certain enzymes, in 8 adults who developed bronchiolitis obliterans syndrome (a type of lung scarring) after a donor stem cell transplant. The goal was to see if the drug could stop the lung damage from getting worse. The study was stopped early, so results are limited.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.