Spine surgeons test dye to check their work Mid-Surgery
NCT ID NCT07363759
First seen Jan 25, 2026 · Last updated Jun 22, 2026 · Updated 25 times
Summary
This study tested whether injecting a contrast dye into the disc space during TLIF spine surgery helps surgeons see if they have removed enough disc material. 56 patients having lumbar fusion for degenerative spine disease were randomly assigned to either just take a picture after dye injection or use that picture to guide additional disc removal. The goal was to see if the dye feedback leads to better disc space clearance and patient outcomes.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Rush University Medical Center
Chicago, Illinois, 60612, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ISOVUE-300 contrast dye
What this could lead to
If successful, this technique could help spine surgeons perform more thorough disc removal during fusion surgery, potentially improving patient outcomes.
What could go wrong
This is a small, completed study with 56 patients. The contrast dye is used only for imaging feedback, not as a treatment, so any benefit is limited to surgical precision.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.