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Promising drug targets Tough-to-Treat leukemia in small trial

NCT ID NCT06648889

First seen Jan 20, 2026 · Last updated Apr 30, 2026 · Updated 12 times

Summary

This study tests a drug called isatuximab in 40 adults with a rare and aggressive blood cancer (T-cell acute lymphoblastic leukemia, or T-ALL) that has returned or not responded to standard treatment. The drug targets a protein (CD38) on the cancer cells to help the immune system attack them. The goal is to see if it can shrink the cancer or clear it from the bone marrow, and to check for side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Charité Berlin, Campus Benjamin Franklin, Department of Hematology, Oncology and Tumorimmunologyt Hämatologie

    RECRUITING

    Berlin, 12203, Germany

    Contact

    Contact

  • Goethe University Hospital Frankfurt, Department of Medicine, Hematology and Oncology

    RECRUITING

    Frankfurt am Main, 60580, Germany

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Klinikum Carl Gustav Carus Dresden, Medizinische Klinik und Poliklinik I

    RECRUITING

    Dresden, 01307, Germany

    Contact

    Contact

  • Klinikum Oldenburg AöR, Universitätsklinik für Innere Medizin - Onkologie und Hämatologie

    RECRUITING

    Oldenburg, 26135, Germany

    Contact

    Contact

  • Robert-Bosch-Krankenhaus; Abteilung für Hämatologie, Onkologie und Palliativmedizin

    RECRUITING

    Stuttgart, 70376, Germany

    Contact

    Contact

  • University Hospital Augsburg, II. Medizinischen Klinik, Hämatologie, internistische Onkologie und Hämostaseologie

    RECRUITING

    Augsburg, 86156, Germany

    Contact

    Contact

  • University Hospital Düsseldorf, Department of Hematology, Oncology and Clinical Immunology

    RECRUITING

    Düsseldorf, 40225, Germany

    Contact

    Contact

  • University Hospital Erlangen AöR, Department of Medicine 5

    RECRUITING

    Erlangen, 91054, Germany

    Contact

    Contact

  • University Hospital Hamburg-Eppendorf, Department of Medicine II

    RECRUITING

    Hamburg, 20251, Germany

    Contact

    Contact

  • University Hospital Heidelberg, Department V, Hematology, Oncology and Rheumatology

    RECRUITING

    Heidelberg, 69120, Germany

    Contact

    Contact

  • University Hospital Leipzig; Klinik für Hämatologie, Zelltherapie, Hämostaseologie und Infektiologie, Bereich Hämatologie und Zelltherapie

    RECRUITING

    Leipzig, 04103, Germany

    Contact

    Contact

  • University Hospital München-Großhadern, Medizinische Klinik und Poliklinik III

    RECRUITING

    München, 81377, Germany

    Contact

    Contact

  • University Hospital Münster, Medizinische Klinik A / KMT-Zentrum

    RECRUITING

    Münster, 48149, Germany

    Contact

    Contact

  • University Hospital Schleswig-Holstein, Campus Kiel, Medical Department II

    RECRUITING

    Kiel, 24105, Germany

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.