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New combo therapy shows promise for rare brain lining cancer

NCT ID NCT02939300

First seen Nov 14, 2025 · Last updated May 23, 2026 · Updated 28 times

Summary

This study tested a combination of two immunotherapy drugs, ipilimumab and nivolumab, in 18 adults with leptomeningeal metastases—cancer that has spread to the fluid and lining around the brain and spinal cord. The main goal was to see how long participants lived and what side effects occurred. The treatment aims to control the disease rather than cure it, as ongoing management is typically needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

  • Massachusetts general Hospital

    Boston, Massachusetts, 02114, United States

Conditions

Explore the condition pages connected to this study.