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New hope for young CLL patients: drug cocktail aims for deep remission

NCT ID NCT02158091

First seen Feb 15, 2026 · Last updated Jun 18, 2026 · Updated 17 times

Summary

This study tests a new drug, IPI-145, added to standard chemotherapy (FCR) for younger adults (18-65) with untreated chronic lymphocytic leukemia (CLL). The goal is to see if the combination is safe and can wipe out even tiny traces of cancer (MRD-negative remission). 32 participants will be followed for side effects and treatment response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Isreal Deaconess Medical Center

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.