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Which lens formula works best for cataract patients with a curved cornea?

NCT ID NCT07346456

Knowledge-focused Sponsor: Second Affiliated Hospital of Xi'an Jiaotong University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 102 cataract patients whose corneas have a higher-than-normal back curve (posterior corneal elevation ≥15 µm). Researchers compared 13 different formulas used to calculate the right lens power for surgery, to see which one gives the most accurate vision results. The goal is to help surgeons pick the best formula for these patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help eye surgeons choose the best formula for cataract patients with a specific corneal shape, improving their vision after surgery.
What could go wrong
This is a small observational study (102 people) that only looks back at results, not a controlled trial. The findings may not apply to all patients or surgeons.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

102 people

The number who actually took part.

Started

Apr 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

From June 2024 to January 2025, patients who visited our hospital, were diagnosed with age-related cataract, and underwent cataract surgery.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Meeting the indications for cataract surgery, and undergoing Phacoemulsification + IOL implantation performed by the same surgeon. * Preoperative biometry performed with IOLMaster 700 and Pentacam AXL, with a posterior corneal elevation greater than 15 μm within the central 5 mm zone on Scheimpflug imaging, and a central corneal thickness \> 500 μm. * Surgery completed successfully without any intraoperative or postoperative complications. * Postoperative subjective refraction performed at 1 month after surgery by the same experienced optometrist. Exclusion Criteria: * Patients with pterygium, corneal diseases, glaucoma, uveitis, or fundus diseases (such as macular edema, retinal detachment), excluding high myopia. * History of ocular trauma or previous intraocular surgery. * Occurrence of intraoperative or postoperative complications, such as iris injury, posterior capsule rupture, IOL dislocation, vitreous prolapse, or vitreous hemorrhage. * Postoperative best corrected visual acuity (BCVA) worse than 0.5. * Difference between postoperative subjective refraction and preoperative target refraction greater than 2.00 D. * Incomplete measurement data.

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Conditions

The condition(s) this trial relates to.

cataract

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

The comparison of iol formulas in eyes with pce≥15UM undergoing cataract surgery

Contacts and locations

Locations

  • Department of Ophthalmology, The Second Affiliated Hospital of Xi'an Jiaotong University

    Xi'an, Shaanxi, China

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