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One-Shot spine injection could ease hip fracture pain

NCT ID NCT05920642

Symptom relief Sponsor: University Hospital Ostrava Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a single injection of morphine into the spinal fluid can provide better pain relief after hip fracture surgery than standard painkillers. Researchers enrolled 82 older adults (ages 60-90) undergoing surgery for a broken hip. They compared pain levels, need for extra pain medication, and breathing side effects between the two groups.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
morphine
What this could lead to
If it works, this could offer a simple, single-dose way to better manage pain after hip fracture surgery, reducing the need for multiple painkillers.
What could go wrong
This is a small, single-center study with only 82 participants. The results may not apply to all patients, and there is a risk of breathing problems with spinal morphine.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

82 people

The number who actually took part.

Started

Sep 2023

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 to 90 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * signed informed consent * 60 to 90 years of age * surgical treatment of proximal femur fracture * The American Society of Anesthesiologists (ASA) classification I to III * spinal anesthesia used for the operation Exclusion Criteria: * general anesthesia used for the operation * allergy to opioids * high risk of respiratory depression

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Conditions

The condition(s) this trial relates to.

femoral neck fracture hip fracture Proximal Femoral Fractures

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Proximal femur fracture

Contacts and locations

Locations

  • University Hospital Ostrava

    Ostrava, Moravian-Silesian Region, 70852, Czechia

More trials for these conditions

Other studies related to the condition(s) this trial covers.