Can a supplement soothe aching knees? small trial hints at relief
NCT ID NCT07658950
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a dietary supplement called INTOFINE-JOINT SUPPORT in 33 adults aged 40-60 with mild knee osteoarthritis. Participants took the supplement for 60 days, and researchers measured changes in pain, stiffness, and physical function using standard questionnaires and tests. The goal was to see if the supplement could safely improve knee joint health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- INTOFINE-JOINT SUPPORT dietary supplement
- What this could lead to
- If it works, this supplement could offer a natural option to ease knee pain and stiffness for people with mild osteoarthritis.
- What could go wrong
- This was a very small, single-arm trial with no placebo group, so results may be due to chance or bias. The supplement is not a cure and effects may be modest.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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33 people
The number who actually took part.
- Started
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Jan 2026
- Finished
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Mar 2026
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male and female volunteers aged 40-60 years with symptoms of mild knee joint dysfunction; total WOMAC scores ranging from 20 to 32 points, and VAS scores within 2-4 points. * In good general health, free from hypertension, diabetes mellitus, systemic diseases and other chronic underlying diseases. * No documented history of allergy to any ingredients of the test product. * Able to strictly follow the requirements and time schedule of the study protocol, and voluntarily sign the informed consent form. Exclusion Criteria: * Subjects aged less than 40 years or more than 60 years. * Those suffering from severe primary diseases involving cardiovascular and cerebrovascular systems, liver, kidney, hematopoietic system and other vital organs. * Individuals who have received knee joint surgery within one year. * Subjects who underwent intra-articular injection within the past 3 months. * Those who have taken anti-arthritic medications (including analgesic drugs) within the preceding one month. * Patients clinically diagnosed with gout or hyperuricemia. * Females who are pregnant, breastfeeding, or planning to conceive within the next two months. * Subjects with severe hepatic or renal insufficiency, hemorrhagic diseases, or those taking anticoagulant drugs. * Participants currently or within the last one month enrolled in other clinical trials related to the tested joint site. * The final decision on subject enrollment shall be made by the investigators.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Guangzhou Jinyu Health Examination Center
Guangzhou, Guangdong, China