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Aggressive cholesterol treatment may halt heart disease in younger patients

NCT ID NCT06896708

First seen Jan 05, 2026 · Last updated May 23, 2026 · Updated 26 times

Summary

This study tests whether intensive cholesterol-lowering therapy (targeting very low LDL levels) can slow the growth of artery plaque in adults aged 18-60 with chronic coronary syndrome. About 766 participants will be randomly assigned to either intensive or standard therapy and monitored for plaque changes using CT scans. The goal is to see if a more aggressive approach prevents heart attacks, hospitalizations, or death.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Guangdong Provincial People's Hospital

    RECRUITING

    Guangzhou, Guangdong, 510100, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Eighth Affiliated Hospital of Sun Yat-sen University

    NOT_YET_RECRUITING

    Shenzhen, Guangdong, 518033, China

  • The First Affiliated Hospital of Chongqing Medical University

    NOT_YET_RECRUITING

    Chongqing, Chongqing Municipality, 400015, China

  • The First Affiliated Hospital of Dalian Medical University

    NOT_YET_RECRUITING

    Dalian, Liaoning, 116000, China

  • The Ninth Clinical Medical College of Guangzhou University of Chinese Medicine

    NOT_YET_RECRUITING

    Dongguan, Guangdong, 523000, China

  • The Third Affiliated Hospital of Guangzhou Medical University

    NOT_YET_RECRUITING

    Guangzhou, Guangdong, 510000, China

  • Zhongshan People's Hospital

    NOT_YET_RECRUITING

    Zhongshan, Guangdong, 528400, China

Conditions

Explore the condition pages connected to this study.