Brain training boosts thinking skills in schizophrenia
NCT ID NCT06286202
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a community-based cognitive remediation program for adults with schizophrenia or schizoaffective disorder. Participants do computer exercises and group sessions to improve memory, problem-solving, and social skills. The goal is to see if this helps them function better in daily life. 160 people will take part, with half receiving the program and half continuing usual activities.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 160 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * A diagnosis of schizophrenia or schizoaffective disorder according to Diagnostic and Statistical Manual of Mental Disorders-5th Edition (DSM-V). * Completed at least ten years of formal education with English as the main instructional language. Participants need to be able to converse in English and understand English instructions, as the cognitive remediation program will be conducted in English. Exclusion Criteria: * Known neurological diseases and epilepsy, which affects gains from cognitive remediation. * Unable to speak and understand English. * Hospitalized within the past one month. * Global Assessment of Functioning score of 30 or below, as participants who are too low functioning are unable to benefit from a strategy learning approach.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
5 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Anglican Care Center-Bukit Batok
RECRUITINGSingapore, Singapore
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Anglican Care Center-Hougang
RECRUITINGSingapore, Singapore
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Anglican Care Center-Pasir Ris
NOT_YET_RECRUITINGSingapore, Singapore
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Anglican Care Center-Simei
RECRUITINGSingapore, Singapore
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Anglican Care Center-Yishun
NOT_YET_RECRUITINGSingapore, Singapore
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Other studies related to the condition(s) this trial covers.
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- New schizophrenia drug targets brain glutamate, not dopamine
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- Five-Year safety check for experimental schizophrenia drug
- A shot every few weeks? new drug tested for schizophrenia