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Colon cancer screening study ends early, no results

NCT ID NCT05246839

Knowledge-focused Sponsor: Exact Sciences Corporation Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early This study
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aimed to see if a short video explaining different colorectal cancer screening options (like colonoscopy, FIT, and Cologuard) could help more people get screened. It included 1,823 adults aged 45-70 who had never been screened. However, the study was stopped early and the main question was not answered.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,823 people

The number who actually took part.

Started

Apr 2022

Finished

Jan 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Subjects will be 45 to 70 years of age, inclusive, who are scheduled for a primary care appointment, at average risk for colorectal cancer (CRC), and due for CRC screening. The study will enroll approximately 1,851 subjects.

Ages

45 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Participant is 45 to 70 years of age, inclusive. 2. Participant presents for a primary care appointment. 3. Participant understands the study procedures and can provide informed consent to participate in the study and authorization for release of relevant protected health information (PHI) to the study Investigator. 4. Participant has never been screened for CRC. Exclusion Criteria: 1. Participant has symptoms or signs that require immediate, or near-term referral for diagnostic or therapeutic colonoscopy. 2. Participant is due for CRC screening within three months and is already scheduled for colonoscopy. 3. Participant has a personal history of CRC or colonic adenomatous or sessile serrated polyps. 4. Participant has a personal history of inflammatory bowel disease. 5. Participant has a family history of CRC in at least one first- or second-degree relative diagnosed prior to age 60 and/or at least 2 first-degree relatives diagnosed with CRC at any age. 6. Participant has a personal diagnosis or family history of any of the following conditions: 1. Familial adenomatous polyposis (also referred to as "FAP", including attenuated FAP and Gardner's syndrome), 2. Hereditary non-polyposis CRC syndrome (also referred to as "HNPCC" or "Lynch Syndrome"), 3. Other hereditary cancer syndromes including, but are not limited to Peutz-Jeghers Syndrome, MYH-Associated Polyposis (MAP), Turcot's (or Crail's) Syndrome, Cowden's Syndrome, Juvenile Polyposis, Neurofibromatosis, or Familial Hyperplastic Polyposis. 7. Participant has a diagnosis of Cronkhite-Canada Syndrome. 8. Participant is current with CRC screening, including gFOBT or FIT within the preceding 12 months, Cologuard within the preceding 3 years, flexible sigmoidoscopy or CT colonography within the preceding 5 years, or colonoscopy within the preceding 10 years. Participants can be enrolled up to 3 months prior to screening due date. 9. Participant has any condition that in the opinion of the Investigators should preclude participation in the study, including comorbid illnesses precluding endoscopic evaluation or that limit life expectancy to less than 10 years.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Colorectal cancer

Contacts and locations

Locations

  • A & U Family Medicine

    Sugarland, Texas, 77479, United States

  • Absolute Clinical Research

    Phoenix, Arizona, 85323, United States

  • Advanced Primary and Geriatric Care

    Rockville, Maryland, 20850, United States

  • Alliance Community Healthcare, INC

    Jersey City, New Jersey, 07302, United States

  • Annapolis Internal Medicine

    Annapolis, Maryland, 21401, United States

  • Ascension DePaul Community Services of New Orleans

    New Orleans, Louisiana, 70118, United States

  • Barrett Clinic

    La Vista, Nebraska, 68128, United States

  • BioPharma Informatic

    Pharr, Texas, 78577, United States

  • Biopharma Informatic

    Los Angeles, California, 90035, United States

  • Center for Medical Research, LLC

    Providence, Rhode Island, 02908, United States

  • Clear Brook Medical Associates

    Houston, Texas, 77089, United States

  • ClinCept, LLC

    Columbus, Georgia, 31904, United States

  • Ellipsis Research Group, LLC

    Brooklyn, New York, 11215, United States

  • Emerald Coast OBGYN

    Panama City, Florida, 32405, United States

  • Herman Clinical Research, LLC

    Suwanee, Georgia, 30013, United States

  • Hightower Clinical OKC

    Oklahoma City, Oklahoma, 73134, United States

  • I.V.A.M Clinical & Investigational Center

    Miami, Florida, 33144, United States

  • ITB Research

    Miami, Florida, 33173, United States

  • Laurelton Heart Specialist PC

    Rosedale, New York, 11422, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

  • Mercado Medical Practice

    Philadelphia, Pennsylvania, 19111, United States

  • Niagara Falls Memorial Medical Center

    Niagara Falls, New York, 14304, United States

  • North Hudson Community Action Corporation

    Union City, New Jersey, 07087, United States

  • Ogden Clinic - Grand View

    Roy, Utah, 84067, United States

  • Ogden Clinic - Mountain View

    Pleasant View, Utah, 84404, United States

  • OnSite Clinical Solutions, LLC

    Charlotte, North Carolina, 28208, United States

  • Pivotal Clinical Research & Associates, LLC

    Marietta, Georgia, 30062, United States

  • Pottstown Medical Specialists Inc

    Pottstown, Pennsylvania, 19464, United States

  • SPICA Clinical Research

    Columbia, South Carolina, 29322, United States

  • Saviers Medical Group

    Port Hueneme, California, 93041, United States

  • Sheridan Medical Center, S.C

    Chicago, Illinois, 60613, United States

  • Skylight Health

    Harrisburg, Pennsylvania, 17109, United States

  • Skylight Health Group

    Aurora, Colorado, 80012, United States

  • Skylight Health Group

    Jacksonville, Florida, 32218, United States

  • South Ogden Family Medicine

    South Ogden, Utah, 84405, United States

  • St. Louis Medical Professionals

    St Louis, Missouri, 63119, United States

  • The Jackson Clinic, PA

    Jackson, Tennessee, 38305, United States

  • Valena Medical Research

    Spring, Texas, 77379, United States

  • Valley Ob-Gyn Clinic, PC

    Saginaw, Michigan, 48602, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.