Blood cancer and heart risk: new study hunts for hidden warning signs
NCT ID NCT06692894
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to understand why people with myelodysplastic syndromes (MDS), a type of blood cancer, are more likely to develop heart disease or stroke. Researchers will measure inflammation-related proteins in the blood of 30 adults with MDS over 6 months to see if these markers can predict heart problems. The goal is to find better ways to detect and manage heart disease risk in MDS patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2024
- Expected to finish
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Nov 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All patients with MDS diagnosed and treated at UVMMC will be eligible.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥18 years * Histologically confirmed diagnosis of MDS by bone marrow biopsy morphology, using the 2022 World Health Organization (WHO) classification for myeloid neoplasms * Eastern Cooperative Oncology Group (ECOG) performance status ≤3 * Expected survival of at least 6 months * Ability to provide consent Exclusion Criteria: * Cases meeting 2022 WHO criteria of MDS with excess blasts 2 as initial diagnosis * Hematopoietic stem cell transplantation expected within 6 months
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Vermont
RECRUITINGBurlington, Vermont, 05495-2038, United States