Study examines which IBD drugs are safer for seniors
NCT ID NCT07250815
First seen Dec 26, 2025 · Last updated Jun 22, 2026 · Updated 21 times
Summary
This study looked at nearly 24,000 older adults (65+) with ulcerative colitis or Crohn's disease to see if certain advanced treatments lead to more infections. Researchers compared patients taking ENTYVIO, TNF-alpha inhibitors, or ustekinumab using Medicare claims data from 2016 to 2025. The goal was to understand the risk of serious and non-serious infections in this age group.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Takeda Site
Cambridge, Massachusetts, 02142, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If this study finds differences in infection rates, it could help doctors choose safer treatments for older patients with inflammatory bowel disease.
What could go wrong
This is an observational study using existing data, so it cannot prove cause and effect. Results may be influenced by unmeasured factors or differences in patient health.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.