New combo therapy eases swelling and boosts mobility in heart failure patients
NCT ID NCT07095764
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether adding manual lymphatic drainage (a gentle massage technique) to early in-hospital cardiac rehabilitation helps people with acute decompensated heart failure. The goal was to reduce leg swelling and improve physical function. Forty stable hospitalized patients took part, and the researchers measured changes in leg swelling, walking ability, and quality of life.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Aug 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients hospitalized with a diagnosis of acute decompensated heart failure * Being clinically stable Exclusion Criteria: * Having diagnosed pulmonary, neurological, renal, liver, gastrointestinal, orthopedic or oncological pathologies * Having cardiomyopathy or congestive pericarditis * Recent heart surgery in the past 6 months * New or suspected thromboembolic event * Presence of open wounds, ulcerations or major dermatological diseases in the lower extremities
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Istanbul University- Cerrahpasa, Cardiology Institute
Istanbul, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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