A checklist for the ER: could a one-page guide save lives in acute heart failure?
NCT ID NCT07727304
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This study tests whether a best-practices checklist can help emergency doctors manage acute heart failure more effectively. The checklist guides assessment, treatment, and decisions about whether to admit or discharge patients. Researchers are introducing the checklist in four large Ontario emergency departments and tracking patient outcomes like death, need for breathing support, and return visits to the ER.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Implementation of the CAEP Acute Heart Failure Best Practices Checklist, a behavioral intervention to guide emergency department care
- What this could lead to
- If the checklist improves patient management and outcomes, it could lead to widespread adoption in emergency departments across Canada, potentially reducing deaths and hospital readmissions.
- What could go wrong
- This is a pilot feasibility study with only 4 hospitals, so results may not apply broadly. The checklist's success depends on doctors actually changing their behavior, which can be challenging.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 5,040 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Aug 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All resident and staff physicians managing patients with AHF in the ED are the primary study participants and this includes emergency, medicine, cardiology, and hospitalists. * The patients that will be included are consecutive adults age \>18 years and who present to the ED with recent onset of or recent increase in shortness of breath due to AHF, as determined by health records review. * Eligibility of patients will be reviewed by the blinded study Steering Committee. * Included will be both patients subsequently admitted to hospital and those discharged from the ED, as both will be impacted by the recommendations of the CAEP AHF Checklist. Exclusion Criteria: * who do not fit the definition of AHF; * if the primary reason for the ED visit was not AHF (e.g. pneumonia, pulmonary embolism); * who have acute myocardial infarction (either ST elevation or non-ST elevation) diagnosed in the ED, because the primary problem for these patients is not heart failure and they require specialized treatment beyond the scope of the Checklist; or * who are considered terminal, with death expected within 60 days.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Ottawa Hospital Research Institute
Ottawa, Ontario, K1Y 4E9, Canada
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Other studies related to the condition(s) this trial covers.
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