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Surgeons try super glue to seal bile leaks after liver parasite surgery

NCT ID NCT06612229

Disease control Sponsor: Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new surgical technique for people with liver echinococcosis (a parasitic infection) who develop bile leaks after surgery. The method uses a special medical glue to seal the leak, aiming to reduce complications and speed up recovery. Researchers will track how often leaks close and how much treatment costs, involving 200 participants in Uzbekistan.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
medical cyanoacrylate glue
What this could lead to
If successful, this could provide a safer, more effective way to repair bile leaks during liver surgery for echinococcosis, reducing complications and recovery time.
What could go wrong
This is a single-center study with no control group, so results may not apply broadly. The glue technique is new and may carry risks like infection or failure to stop the leak.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 200 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2023

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age under 18 years; * Informed consent for inclusion in the study; * The presence of liver echinococcosis, for which conservative surgical treatment will be performed; * The presence of the entire spectrum of necessary preoperative diagnostic measures; * A full description of all stages of surgical intervention, indicating the type of intervention (open or laparoscopic surgery, location and size of the echinococcal cyst in the liver, type of antiparasitic treatment, presence or absence of a biliary fistula in the residual cavity, actions taken in relation to the fistula, the option of eliminating the residual cavity and drainage; * Availability of objective data on the characteristics of the postoperative course, including dynamic indicators of the patient\'s condition, temperature, amount and nature of discharge through the drainage, the time of drainage removal, the type of complications (if any) and the method of their treatment, the duration of the hospital period, data on the characteristics of the posthospital period up to 3 months of observation; * Absence of concomitant pathology that may affect the outcome of the surgery. Exclusion Criteria: * Age under 18 years; * Refusal to participate in the study; * Extrahepatic echinococcosis without liver damage; * Absence of the full range of preoperative diagnostic data; * Difficulties with objective analysis of the features of the performed surgical treatment; * Incomplete data on monitoring the postoperative hospital and remote (up to 3 months) period; * The presence of concomitant pathology that may affect the outcome of the operation.

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Conditions

The condition(s) this trial relates to.

Biliary Fistula echinococcosis Echinococcosis, Hepatic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Biliary fistula Echinococcosis, hepatic

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Republican specialized scientific and practical medical center of surgery named after academician V.Vakhidov

    RECRUITING

    Tashkent, 100000, Uzbekistan

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