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New gene therapy shows promise in fight against ovarian cancer

NCT ID NCT03393884

First seen Nov 01, 2025 · Last updated May 25, 2026 · Updated 25 times

Summary

This study tests a new treatment called IMNN-001, a gene therapy that boosts the immune system, given together with standard chemotherapy for people newly diagnosed with advanced ovarian, fallopian tube, or primary peritoneal cancer. The goal is to see if the combination helps keep the cancer from growing longer than chemotherapy alone. About 130 participants are randomly assigned to receive either the combination or standard treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Advent Health

    Orlando, Florida, 32803, United States

  • CHUM

    Montreal, H2X 0A9, Canada

  • Chattanooga Women's Health

    Chattanooga, Tennessee, 37403, United States

  • Gynecologic Oncology Associates (Hoag Hospital)

    Newport Beach, California, 92663, United States

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States

  • Innovative Clinical Research

    Whittier, California, 90603, United States

  • MD Anderson at Cooper

    Camden, New Jersey, 08105, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Mitchell Cancer Institute (University of South Alabama)

    Mobile, Alabama, 36604, United States

  • Monter Cancer Center

    Lake Success, New York, 11042, United States

  • NYU Langone

    New York, New York, 10016, United States

  • NYU Langone, Long Island

    Mineola, New York, 11501, United States

  • Providence Cancer Institute

    Portland, Oregon, 97213, United States

  • Providence Health Care

    Spokane, Washington, 99204, United States

  • Sanford Health

    Sioux Falls, South Dakota, 57104, United States

  • Stephenson Cancer Center - Oklahoma University

    Oklahoma City, Oklahoma, 73104, United States

  • The West Clinic

    Germantown, Tennessee, 38138, United States

  • University of Alabama Birmingham

    Birmingham, Alabama, 35233, United States

  • Washington University School of Medicine in St. Louis

    St Louis, Missouri, 63110, United States

  • Women's Care Florida

    St. Petersburg, Florida, 33701, United States

Conditions

Explore the condition pages connected to this study.