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New cocktail approach for tough pancreatic cancer shows promise

NCT ID NCT03193190

First seen Nov 21, 2025 · Last updated May 20, 2026 · Updated 24 times

Summary

This study tested several combinations of immunotherapy drugs in 341 people with metastatic pancreatic cancer that had spread. The goal was to see if these combos could shrink tumors and control the disease. Participants were split into two groups: those who had not yet received treatment and those who had already tried one type of chemotherapy. The study focused on safety and how well the tumors responded.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • City of Hope Comprehensive Cancer Center

    Duarte, California, 91010, United States

  • Clínica Universidad de Navarra

    Pamplona, Navarre, 31008, Spain

  • Columbia University

    New York, New York, 10032, United States

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Helen Diller Fam Comp Can Ctr

    San Francisco, California, 94158, United States

  • Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

  • Hosp. G. U Gregorio Marañón

    Madrid, 28007, Spain

  • Hospital Universitario Ramon y Cajal

    Madrid, 28037, Spain

  • Hospital Universitario Vall d Hebron

    Barcelona, 08035, Spain

  • Kanagawa Cancer Center

    Kanagawa, 241-8515, Japan

  • Lombardi Cancer Center, Georgetown University

    Washington D.C., District of Columbia, 20007, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53226, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • MorristownMedicalCenter

    Morristown, New Jersey, 07962, United States

  • National Cancer Center Hospital

    Tokyo, 104-0045, Japan

  • National Cancer Center Hospital East

    Chiba, 277-8577, Japan

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Samsung Medical Center

    Seoul, 06351, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Smilow Cancer Hospital at Yale New Haven

    New Haven, Connecticut, 06510, United States

  • Uni of Chicago Medical Center

    Chicago, Illinois, 60637, United States

  • Universitätsklinikum Essen

    Essen, 45122, Germany

Conditions

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