New drug targets Hard-to-Treat cancers in early trial
NCT ID NCT06840119
First seen Feb 01, 2026 · Last updated May 24, 2026 · Updated 23 times
Summary
This study tests a new drug, IMC-R117C, for people with advanced colorectal, esophageal, stomach, or ovarian cancers that have a specific protein (PIWIL1) and a certain immune type (HLA-A*02:01). The goal is to see if the drug is safe and can shrink or control tumors. About 600 participants will receive the drug alone or with other treatments.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Antoni van Leeuwenhoek
RECRUITINGAmsterdam, Netherlands
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Centro Integral Oncologico Clara Campal
RECRUITINGMadrid, Spain
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITINGRoma, Italy
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Hospital HM Nou Delfos
RECRUITINGBarcelona, Spain
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Hospital Universitario Fundacion Jimenez Diaz
RECRUITINGMadrid, Spain
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Institut Jules Bordet
RECRUITINGAnderlecht, 1070, Belgium
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Peter MacCallum Cancer Centre
RECRUITINGMelbourne, Australia
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St Vincent's Hospital
ACTIVE_NOT_RECRUITINGDarlinghurst, Sydney, NSW 2010, Australia
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UZ Leuven
RECRUITINGLeuven, 3000, Belgium
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Universitaetsklinikum Heidelberg
RECRUITINGHeidelberg, Germany
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Universitair Ziekenhuis Gent
RECRUITINGGhent, Belgium
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VHIO, Vall d'Hebron University Hospital
RECRUITINGBarcelona, Spain
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nstituto Clinico Humanitas
RECRUITINGRozzano, 20089, Italy
Conditions
Explore the condition pages connected to this study.