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MRI scan could replace grueling bike test for cancer surgery patients

NCT ID NCT06544187

First seen Apr 06, 2026 · Last updated Jun 22, 2026 · Updated 12 times

Summary

This study explores whether a magnetic resonance spectroscopy (MRS) scan of the thigh can replace the standard cardiopulmonary exercise test (CPET) for assessing fitness for stomach, esophageal, or pancreatic cancer surgery. The CPET requires patients to cycle to exhaustion, which is physically demanding and not possible for everyone. The MRS scan measures fat levels in thigh muscle, which may correlate with fitness. The study will enroll 56 participants—patients on the surgical pathway and healthy volunteers—to compare MRS results with CPET outcomes and test the reliability of the scan.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospitals of North Midlands NHS Trust

    RECRUITING

    Stoke-on-Trent, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Magnetic Resonance Spectroscopy (MRS) scan

What this could lead to

If it works, this could offer a gentler, more accessible way to assess surgical fitness for patients who cannot do exercise tests.

What could go wrong

This is a small, early-stage study (56 participants) comparing a new method to an established one. The MRS scan may not correlate well enough with exercise test results to replace it.

Conditions

The condition(s) this trial relates to.

esophageal cancer exocrine pancreatic carcinoma gastric cancer malignant pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.