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New hope for relapsed leukemia: IMAGINE trial tests Triple-Drug attack

NCT ID NCT07320235

First seen Jan 11, 2026 · Last updated Apr 30, 2026 · Updated 20 times

Summary

This early-phase trial is testing whether adding the experimental drug imetelstat to standard chemotherapy (azacitidine, with or without venetoclax) can safely help people whose acute myeloid leukemia has returned or not responded to prior treatment. The study involves up to 36 adults at Mount Sinai Hospital and will first find the safest dose, then look for the most effective dose. It is not a cure, but aims to control the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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