Which comes first? study seeks best sequence for IDH-Mutated leukemia in older patients
NCT ID NCT05401097
First seen May 14, 2026 · Last updated May 21, 2026 · Updated 2 times
Summary
This study is for older adults with a specific genetic form of acute myeloid leukemia (IDH-mutated AML) who cannot have strong chemotherapy. It compares two treatment sequences: one starting with a targeted IDH inhibitor followed by a standard combo, and the other starting with the combo followed by the IDH inhibitor. The goal is to see which order works better to control the disease. About 125 people will take part.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
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Locations
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Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210, United States
Contact
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UT Southwestern Medical Center at Dallas
RECRUITINGDallas, Texas, 75235, United States
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Conditions
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