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New cancer drug enters first human trials for Tough-to-Treat tumors

NCT ID NCT04794699

Summary

This is the first study in people testing IDE397, a new oral drug, for advanced solid tumors that have a specific genetic change called MTAP deletion and have stopped responding to standard treatments. The main goals are to find safe doses of IDE397 when given alone and when combined with other cancer drugs, and to see if it shows early signs of helping shrink tumors. The study will enroll about 180 adults to help determine if this experimental treatment should move forward to larger trials.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advent Health

    WITHDRAWN

    Celebration, Florida, 34747, United States

  • Asan Medical Center

    RECRUITING

    Seoul, 05505, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Barbara Ann Karmanos Cancer Institute

    WITHDRAWN

    Detroit, Michigan, 48201, United States

  • CHA University - Bundang Medical Center

    RECRUITING

    Seongnam-si, Gyeonggi-do, 28644, South Korea

    Contact Email: •••••@•••••

  • Centre Eugène Marquis

    RECRUITING

    Rennes, 35000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Chungbuk National University Hospital

    RECRUITING

    Cheongju-si, North Chungcheong, 28644, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Columbia University Medical Center - Herbert Irving Pavilion

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dana Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact Email: •••••@•••••

  • Hoag Memorial Hospital

    RECRUITING

    Newport Beach, California, 92663, United States

  • Honor Health Research Institute

    COMPLETED

    Scottsdale, Arizona, 85258, United States

  • Hospital Universitario 12 de Octubre (H12O)

    RECRUITING

    Madrid, 28041, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Timone

    RECRUITING

    Marseille, Marseille, 13005, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Indiana University Health Hospital

    COMPLETED

    Indianapolis, Indiana, 46202, United States

  • Institut Bergonie

    RECRUITING

    Bordeaux, Bordeaux Cedex, 33076, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Claudius Regaud - IUCT-Oncopole

    RECRUITING

    Toulouse, Cedex 9, 31059, France

    Contact Email: •••••@•••••

  • Instituto Valenciano de Oncología (IVO)

    RECRUITING

    Valencia, 46009, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • LifeSpan - Brown University

    COMPLETED

    Providence, Rhode Island, 02906, United States

  • MD Anderson

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Markey Cancer Center

    WITHDRAWN

    Lexington, Kentucky, 40536, United States

  • NEXT Madrid, Universitary Hospital QuironSAlud

    RECRUITING

    Madrid, 28223, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Cancer Center

    RECRUITING

    Goyang-si, Gyeonggi-do, 10408, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Cheng Kung University Hospital

    RECRUITING

    Tainan, Tainan, 704, Taiwan

    Contact Email: •••••@•••••

  • National Taiwan University Hospital

    RECRUITING

    Taipei, Taipei, 100, Taiwan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Next Oncology

    COMPLETED

    San Antonio, Texas, 78229, United States

  • Orlando Health Cancer Institute

    RECRUITING

    Orlando, Florida, 32806, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Providence Medical Group

    WITHDRAWN

    Santa Rosa, California, 95403, United States

  • Rockefeller Cancer Institute

    RECRUITING

    Little Rock, Arkansas, 72205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • START Madrid-HM - Centro Integral Oncológico Clara Campal (CIOCC)

    RECRUITING

    Madrid, 28050, Spain

    Contact Email: •••••@•••••

  • Sarah Cannon Research Institute

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact Phone: •••-•••-••••

  • Sevrance Hospital

    RECRUITING

    Seoul, 03722, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Southern Oncology Clinical Research Unit

    COMPLETED

    Bedford Park, South Australia, 05042, Australia

  • Stephenson Cancer Center

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Swedish Cancer Institute

    RECRUITING

    Seattle, Washington, 98104, United States

  • The Kinghorn Cancer Centre, St Vincent's Health Network Sydney

    RECRUITING

    Darlinghurst, New South Wales, 02010, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitaetsklinikum Hamburg-Eppendorf (UKE)

    RECRUITING

    Hamburg, 20246, Germany

    Contact Email: •••••@•••••

  • Vall Hebron Institute of Oncology

    RECRUITING

    Barcelona, 08035, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Weill Cornell Medical College

    COMPLETED

    New York, New York, 10065, United States

Conditions

Explore the condition pages connected to this study.