Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Healthy volunteers test new drug capsule with and without food

NCT ID NCT07254286

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study looked at how taking a new drug called icovamenib with or without food changes the way the body absorbs it. Sixty healthy adults took the capsule in different conditions to measure drug levels in the blood. The goal was to gather information for future dosing, not to treat any disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

60 people

The number who actually took part.

Started

Sep 2025

Finished

Jan 2026

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Informed Consent and Compliance 1. Must be able to understand a written informed consent, which must be obtained prior to initiation of study procedures. 2. Must be willing and able to comply with all study requirements. Baseline Characteristics 3. Healthy males or non-pregnant, non-lactating healthy females. 4. Body mass index (BMI) of 18.0 to 27.0 kg/m2 as measured at screening. 5. HbA1c ≤ 5.6%. 6. Fasting glucose ≤ 99 mg/dL. Exclusion Criteria: Medical/Surgical History and Mental Health 1. Mean QTcF interval greater than 440 msec on triplicate ECGs. Use of prescription or over-the-counter (OTC) medications known to significantly prolong the QT or QTcF interval. 2. History of hypertension or untreated hypertension (systolic blood pressure (BP) \>140 mmHg and/or diastolic BP \>90 mmHg). 3. Known self or family history (first-degree relative) of multiple endocrine neoplasia Type 1. 4. History of stomach or intestinal surgery or resection (except appendectomy, hernia and/or cholecystectomy). Diagnostic assessments. 5. Clinically significant abnormal clinical chemistry, hematology, coagulation or urinalysis as judged by the investigator. 6. History or evidence of hepatitis C virus (HCV), or hepatitis B virus (HBV) infection or human immunodeficiency virus (HIV) at screening. 7. Estimated creatinine clearance (CLcr) of \<90 mL/min. 8. AST, ALT or bilirubin \> ULN at screening. 9. Prior Study Participation. 10. Subjects who have received any IMP in a clinical research study within 5 half-lives or within 30 days prior to first dose. 11. Prior and Concomitant Medication. 12. Subjects who are taking, or have taken, any prescribed or OTC drug or herbal remedies (other than HRT/hormonal contraception and up to 4 g per day acetaminophen) in the 14 days before first study medication administration. 13. Currently dieting (formal weight loss program) and/or are currently using or have used within 2 months of screening any drugs for weight management. 14. Received prior menin inhibitor treatment.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Healthy volunteer are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Quotient Sciences - Miami, Inc.

    Miami, Florida, 33126, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.