Could a simple ice water flush prevent pancreatitis after a common procedure?
NCT ID NCT07677397
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This trial investigates whether flushing the bile duct opening with ice-cold water after an ERCP procedure can reduce the chance of developing pancreatitis, a frequent complication. Researchers will compare patients who receive the flush to those who do not, looking at pancreatitis rates, recovery time, and hospital stays. The study enrolls adults scheduled for an endoscopic sphincterotomy at participating hospitals.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- ice-cold water flush
- What this could lead to
- If effective, this simple, low-cost technique could become a standard step during ERCP to prevent a common and painful complication.
- What could go wrong
- This is an early-stage trial with 210 participants, so results may not apply broadly. The procedure is safe, but its effectiveness over existing prevention methods is unproven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 210 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All adults (agesld 18 years old) scheduled for an endoscopic sphincterotomy at the participating hospitals. Exclusion Criteria: * Patients with missing data, acute or chronic pancreatitis, pancreatic cancer, or those unable to provide informed consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- One-Time drug infusion may shield the pancreas after ERCP
- A 4-Hour IV drip could stop a common Post-ERCP complication
- Common painkiller may prevent pancreatitis after bile duct procedure
- Can a simple pill prevent pancreatitis after ERCP? new study tests two drugs
- When to remove pancreatic stents? new trial aims to find out
- Can a double dose stop Post-Procedure pancreatitis?