New hope for tough stomach cancers: targeted drug IBI343 in Late-Stage trial
NCT ID NCT06238843
First seen May 19, 2026 · Last updated May 24, 2026 · Updated 2 times
Summary
This phase 3 study tests a new drug called IBI343 against standard treatments for people with advanced stomach or gastroesophageal junction cancer that has not responded to prior therapies. The trial enrolls about 464 participants whose tumors have a specific marker (CLDN18.2) and lack another (HER2-negative). The goal is to see if IBI343 can slow cancer growth or improve survival compared to current options.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for UNRESECTABLE OR METASTATIC GASTRIC OR GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Locations
-
Affiliated Zhongshan hospital of Dalian university
Dalian, Liaoning, 116001, China
-
Anhui Provincial Hospital
Hefei, Anhui, 230001, China
-
Beijing Cancer Hospital
Beijing, Beijing Municipality, 100142, China
-
Cancer Institute Hospital of JFCR
Koto, Tokyo, 135-8550, Japan
-
Chenzhou No.1 People's Hospital
Chenzhou, Hunan, 423000, China
-
Chiba Cancer Center
Chiba, Tiba [Chiba], 260-8717, Japan
-
Dongguan People's Hospital
Dongguan, Guangdong, 523018, China
-
Fujian Cancer Hospital
Fuzhou, Fujian, 350014, China
-
Fujian Medical University Union Hospital
Fuzhou, Fujian, 350000, China
-
Gansu Provincial Cancer Hospital
Lanzhou, Gansu, 730050, China
-
General Hospital of Ningxia Medical University
Yinchuan, Ningxia, 750003, China
-
Gifu University Hospital
Gifu, Gifu, 501-1194, Japan
-
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, 519041, China
-
Guanxi Medical University Cancer Hospital
Nanning, Guangxi, 530000, China
-
Gunma Prefectural Cancer Center
Ota-Shi, Gunma, 373-8550, Japan
-
Harbin Medical University Cancer Hospital
Harbin, Heilongjiang, 150081, China
-
Henan Cancer hospital
Zhengzhou, Henan, 450008, China
-
Henan Provincial People's Hospital
Zhengzhou, Henan, 463599, China
-
Hubei Cancer Hospital
Wuhan, Hubei, 430079, China
-
Hunan Cancer Hospital
Changsha, Hunan, 410000, China
-
Hunan Provincial Cancer Hospital
Changsha, Hunan, 410031, China
-
Hyogo Cancer Center
Akashi, Hyōgo, 673-8558, Japan
-
Jiangsu Cancer Hospital
Nanjing, Jiangsu, 210009, China
-
Jinan Central Hospital
Jinan, Shandong, 250013, China
-
Jinhua Municipal Central Hospital
Jinhua, Zhejiang, 321000, China
-
Kanagawa Cancer Center
Yokohama, Kanagawa, 241-8515, Japan
-
Kindai University Hospital
Osakasayama-Shi, Osaka, 589-8511, Japan
-
Kobe City Medical Center General Hospital
Kobe, Hyōgo, 650-0047, Japan
-
Kochi Health Sciences Center
Kochi, Koti [Kochi], 781-8555, Japan
-
Linyi People's Hospital
Linyi, Shandong, 276002, China
-
Lu'an People's Hospital of Anhui Province
Lu'an, Anhui, 237000, China
-
Nanjing Drum Tower Hospital
Nanjing, Nanjing, 210008, China
-
Nanyang Central Hospital
Nanyang, Henan, 473005, China
-
National Cancer Center Hospital
Tokyo, Tsukiji, Chuo-ku, 104-0045, Japan
-
National Cancer Center Hospital East
Kashiwa-shi, Chiba, 277-8577, Japan
-
National Hospital Organization Kure Medical Center and Chugoku Cancer Center
Kure, Hirosima [Hiroshima], 737-0023, Japan
-
National Hospital Organization Kyushu Cancer Center
Fukuoka, Hukuoka [Fukuoka], 811-1395, Japan
-
National Hospital Organization Shikoku Cancer Center
Matsuyama, Ehime, 791-0280, Japan
-
Northern Jiangsu People's Hosipital
Yangzhou, Jiangsu, 225001, China
-
Osaka Prefectural Hospital Organization - Osaka International Cancer Institute
Osaka, Osaka, 541-8567, Japan
-
Peking Union Medical College Hospital
Beijing, Beijing Municipality, 100032, China
-
Puyang People's Hospital
Puyang, Henan, 457005, China
-
Qinghai University Affiliated Hospital
Xining, Qinghai, 810012, China
-
Renji Hospital, Medical College, Shanghai Jiaotong University
Shanghai, Shanghai Municipality, 200001, China
-
Saitama Medical University - International Medical Center
Hidaka-Shi, Saitama, 350-1298, Japan
-
Saitama Prefectural Cancer Center
Kitaadachi-Gun, Saitama, 362-0806, Japan
-
Shandong Cancer Hospital
Jinan, Shandong, 250117, China
-
Shanxi Bethune Hospital
Taiyuan, Shanxi, 030032, China
-
Shanxi Cancer hospital
Taiyuan, Shanxi, 030013, China
-
Shengjing Hospital of China Medical University
Shenyang, Liaoning, 110000, China
-
Sichuan Cancer Hospital
Chengdu, Sichuan, 610041, China
-
Sir Run Run Shaw Hospital Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310016, China
-
St. Marianna University Hospital
Kawasaki, Kanagawa, 216-8511, Japan
-
Taizhou Central Hospital
Taizhou, Zhejiang, 318001, China
-
Taizhou Hospital of Zhejiang Province
Taizhou, Zhejiang, 317099, China
-
Teine Keijinkai Hospital
Sapporo, Hokkaido, 006-8555, Japan
-
The 2nd Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, 150001, China
-
The Affiliated Hospital of Inner Mongolia Medical University
Hohhot, Inner Mongolia, 750306, China
-
The Affiliated Hospital of Qingdao University
Qingdao, Shandong, 266003, China
-
The First Affiliated Hospital Of XI'AN Jiaotong University
Xi'an, Shaanxi, 710061, China
-
The First Affiliated Hospital of Anhui Medical University
Hefei, Anhui, 230022, China
-
The First Affiliated Hospital of Bengbu Medical University
Bengbu, Anhui, 233004, China
-
The First Affiliated Hospital of Fujian Medical University
Fuzhou, Fujian, 350000, China
-
The First Affiliated Hospital of USTC /Anhui Provincial Hospital
Hefei, Anhui, 230001, China
-
The First Affiliated Hospital of Wannan Medical College
Wuhu, Anhui, 241001, China
-
The First Affiliated Hospital of Xinxiang Medical University
Weihui, Henan, 453100, China
-
The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310003, China
-
The First Hospital of Jiaxing
Jiaxing, Zhejiang, 314001, China
-
The First Hospital of Zhengzhou University
Zhengzhou, Henan, 450052, China
-
The First People's Hospital of Changzhou
Changzhou, Jiangsu, 213000, China
-
The First People's Hospital of Lianyunguang
Lianyungang, Jiangsu, 222061, China
-
The Fourth Hospital of Hebei Medical University
Shijiazhuang, Hebei, 050035, China
-
The People's Hospital of Guangxi Zhuang Autonomous Region
Nanning, Guangxi, 530000, China
-
The Second Affiliated Hospital of Nanchang University
Nanchang, Jiangxi, 330000, China
-
The Second Affiliated Hospital of Soochow University
Suzhou, Jiangsu, 215004, China
-
The Seventh Affiliated Hospital,Sun Yat-sen University
Guangdong, Shenzhen, 518107, China
-
The Third Bethune hospital of Jilin University
Changchun, Jilin, China
-
The University of Osaka Hospital
Suita-shi, Osaka, 565-0871, Japan
-
The firsr Affiliated hospital of Wenzhou medical university
Wenzhou, Zhejiang, 325000, China
-
The first affiliated Hospital of Soochow University
Suzhou, Jiangsu, 215006, China
-
The second hospital of Dalin medical university
Dalian, Liaoning, 116027, China
-
The second hospital of Lanzhou university
Lanzhou, Gansu, 730030, China
-
Tokyo Metropolitan Komagome Hospital
Bunkyō-Ku, Tokyo, 113-8677, Japan
-
Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, 430000, China
-
University of Tokyo Hospital
Bunkyō-Ku, Tokyo, 113-8655, Japan
-
West China Hospital of Sichuan University
Chengdu, Sichuan, 610041, China
-
Xiangyang Central Hospital
Xiangyang, Hubei, 441021, China
-
Xinyang Central Hospital
Xiangyang, Henan, 464300, China
-
Xuzhou Central Hospital
Xuzhou, Jiangsu, 221111, China
-
Yokohama City University Medical Center
Yokohama, Kanagawa, 232-0024, Japan
-
Yueyang Central Hospital
Yueyang, Hunan, 414000, China
-
Yunnan Cancer Hospital
Kunming, Yunnan, 650100, China
-
Zhejiang Cancer Hospital
Hangzhou, Zhejiang, 310005, China
-
Zhejiang Provincial People's Hospital
Hangzhou, Zhejiang, 314408, China
-
Zhuzhou Central Hospital
Zhuzhou, Hunan, 412007, China
Conditions
Explore the condition pages connected to this study.