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New drug IBI3014 enters first human tests for Hard-to-Treat cancers

NCT ID NCT06974812

First seen Jan 30, 2026 · Last updated Jun 19, 2026 · Updated 20 times

Summary

This early-phase trial is testing an experimental drug called IBI3014 in 250 adults with advanced solid tumors that cannot be surgically removed. The study aims to find the safest dose and check whether the drug can shrink tumors. Participants receive IBI3014 by IV every three weeks at different dose levels.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fujian cancer hospital

    RECRUITING

    Fuzhou, Fujian, 350014, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hunan Cancer Hospital

    RECRUITING

    Changsha, Hunan, 410000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Shanghai Pulmonary Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, 200433, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IBI3014 (an experimental drug given by IV infusion every 3 weeks)

What this could lead to

If it works, this could point toward a new treatment option for people with advanced solid tumors that cannot be removed by surgery.

What could go wrong

This is a very early, first-in-human study, so the drug may not shrink tumors or may cause unexpected side effects. Success in this small trial does not guarantee broader benefit.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.